Serious problems related to the contemporary conflict is an internal conflict growth that could trigger separatist movements because of political and regional interests; including the social conflict happening in some countries against the backdrop of social dynamics, culture, primordial, ethnic, race, and religion. The pattern of divide et impera or divide the components of the internal nation is an effective way to destroy a country. As it happened in the Arab Spring phenomenon, the political and security turmoil in Egypt, as well as the civil war in Iraq, Afghanistan, Libya, and Syria to prove the existence of a pattern of the conflict. The use and dissemination of harmful materials of CBRN-E could potentially pose a threat to the security and safety of mankind. 12 Science and technology development in the field of Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) simul­ taneously with the advancement of trans­ portation and communication of information has increased the control, utilization, and the spread of which it essentially can be used for the benefit of human welfare. However, those hazardous materials have the potential to threaten human security and safety when it is controlled by the irresponsible party. The vulnerability is confirmed that there are still some countries producing hazardous materials and are not transparent. It poses a threat to other countries.