The world still faces several epidemics of infectious, dangerous diseases to human being. The World Health Organization (WHO) continues to warn the world that infectious, dangerous diseases to human beings is not yet resolved even it tends increasingly widespread. Almost every year has found one to three variants of new infectious diseases in humans or an old disease reappeared. There is a tendency for respiratory infections in humans increases with the emergence of new cases in the population, as indicated in certain regions. WHO has announced a number of disease that still threatens human being, namely Dengue Fever, Tuberculosis (TBC), Human Immunodeficiency Virus / Acquired Immune Deficiency Syndrome (HIV / AIDS), BSE (Mad Cow) or Variant Creutzfeldt-Jakob Disease (VCJD), Avian Influenza (H5N1) or Avian Influenza, Severe Acute Respiratory Syndrome (SARS), Swine Flu / H1N1 flu virus), Middle East Respiratory Syndrome (MERS), Ebola and Avian Influenza (H7N9) or new variants of bird flu, as well as Zika virus. Geographically, Asia, Sub-Saharan Africa, Latin America and the Caribbean are identified by the WHO as regions that are vulnerable to the emergence of a dangerous disease. The trend of respiratory infections in humans is increasing with the emergence of new cases. 19